Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | EPOR | P19235 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6500033 | 0.85 | ACHE (0.54) | BCHETSHRHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL3322548 | 0.82 | KCNH2 (0.56) | BCHEKDM4EACHE | |
| SCHEMBL4367270 | 0.81 | ACHE (0.60) | BCHETSHRMAPK1ACHECALM1 | |
| Hydrochloric Acid SCHEMBL31687479 | 0.81 | KCNH2 (0.55) | BCHEKDM4EACHE | |
| SCHEMBL6505492 | 0.81 | TSHR (0.58) | BCHETSHRHSD17B10MAPK1KDM4E | |
| SCHEMBL11705881 | 0.78 | TSHR (0.57) | BCHETSHRHSD17B10MAPK1KDM4E | |
| SCHEMBL5947410 | 0.78 | BCHE (0.62) | BCHETSHRHSD17B10MAPK1KDM4E | |
| SCHEMBL10683775 | 0.77 | BCHE (0.58) | BCHETSHRMAPK1KDM4E | |
| SCHEMBL11454505 | 0.77 | TAAR1 (0.57) | BCHETSHRMAPK1ACHECALM1 | |
| SCHEMBL15702639 | 0.76 | TSHR (0.60) | BCHETSHRHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | BCHE 945/4885TSHR 3179/4885HSD17B10 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.