Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 8/20 | 0.59 |
| ▸ | F10 | P00742 | 6/20 | 0.56 |
| ▸ | F2 | P00734 | 5/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462462 | 0.80 | CHRM3 (0.61) | F10F2CHRM2CHRM3PRSS1 | |
| SCHEMBL11236082 | 0.80 | F10 (0.69) | F10F2CHRM2CHRM3PRSS1 | |
| SCHEMBL6496580 | 0.80 | CCR8 (0.56) | CCR8CHRM2CHRM3KCNH2OPRM1 | |
| SCHEMBL6504157 | 0.78 | CCR8 (0.66) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL7066463 | 0.77 | CYP3A4 (0.62) | CCR8KCNH2OPRM1 | |
| SCHEMBL6507204 | 0.77 | CCR8 (0.57) | CCR8CHRM2CHRM3KCNH2OPRM1 | |
| SCHEMBL7068037 | 0.77 | CCR8 (0.57) | CCR8CHRM2CHRM3KCNH2OPRM1 | |
| SCHEMBL1845087 | 0.76 | CCR8 (0.62) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL7068005 | 0.76 | OPRM1 (0.84) | CCR8KCNH2OPRM1 | |
| SCHEMBL6506424 | 0.76 | CCR8 (0.63) | CCR8KCNH2MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | CCR8 1/4885F10 2774/4885F2 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.