Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909458 | 0.85 | VCP (0.38) | ATMTDP1MAPTPKMMAPK1 | |
| SCHEMBL4577560 | 0.82 | ATM (0.36) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL28774035 | 0.77 | ALDH1A1 (0.36) | ATMTDP1MAPTMAPK1ALDH1A1 | |
| SCHEMBL27818989 | 0.77 | ALDH1A1 (0.33) | TDP1ALDH1A1HIF1ACYP3A4 | |
| SCHEMBL1822058 | 0.74 | ALDH1A1 (0.46) | ATMTDP1MAPTPKMMAPK1 | |
| SCHEMBL27684781 | 0.73 | ALDH1A1 (0.36) | ATMTDP1MAPTMAPK1ALDH1A1 | |
| SCHEMBL4902091 | 0.73 | CA12 (0.34) | TDP1MAPTMAPK1ALDH1A1HIF1A | |
| SCHEMBL28738082 | 0.73 | HTT (0.38) | TDP1MAPTPKMALDH1A1CYP3A4 | |
| SCHEMBL9304210 | 0.70 | ALDH1A1 (0.33) | ATMTDP1MAPTMAPK1ALDH1A1 | |
| SCHEMBL3279026 | 0.69 | GRIN2D (0.37) | MAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| CN-112867721-B | STING agonistic compounds | 小野药品工业株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-112867721-A | STING agonistic compounds | 小野药品工业株式会社 | 2021-05-28 | — | — | CN | disclosed |
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |