SCHEMBL9304210

SCHEMBL9304210

O=[N+]([O-])c1[c]cc(F)c(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.33
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
HIF1A Q16665 2/20 0.33
ALOX15 P16050 2/20 0.33
TSHR P16473 2/20 0.33
SIRT6 Q8N6T7 1/20 0.33
HPGD P15428 1/20 0.33
TXNRD1 Q16881 1/20 0.33
TXNRD3 Q86VQ6 1/20 0.33
TXNRD2 Q9NNW7 1/20 0.33
POLB P06746 1/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
ATM Q13315 1/20 0.32
PDE7A Q13946 1/20 0.31
LMNA P02545 2/20 0.30
HTT P42858 2/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145308 0.85 ALDH1A1 (0.35) ALDH1A1CYP3A4TDP1HIF1AALOX15
SCHEMBL27818989 0.81 ALDH1A1 (0.33) ALDH1A1CYP3A4TDP1HIF1AALOX15
SCHEMBL147513 0.81 ALDH1A1 (0.40) ALDH1A1CYP3A4TDP1HIF1AALOX15
SCHEMBL4577560 0.79 ATM (0.36) ALDH1A1TDP1HIF1AATM
SCHEMBL1822058 0.76 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1HIF1AALOX15
SCHEMBL11909458 0.74 VCP (0.38) ALDH1A1CYP3A4TDP1HIF1AMAPT
SCHEMBL27684781 0.74 ALDH1A1 (0.36) ALDH1A1CYP3A4TDP1HIF1AALOX15
SCHEMBL28774035 0.70 ALDH1A1 (0.36) ALDH1A1CYP3A4TDP1HIF1AALOX15
SCHEMBL6506181 0.70 ATM (0.37) ALDH1A1CYP3A4TDP1HIF1AMAPT
SCHEMBL147133 0.70 GPR3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5369116-A Polyfluorinated thiazoline derivative and chemical for controlling noxious organisms containing the same UBE INDUSTRIES, LTD. (JP) 1994-11-29 US disclosed