Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507992 | 0.88 | CA2 (0.51) | CTSLALDH1A1HPGDNPC1GAA | |
| SCHEMBL820939 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HPGDNPC1GAALMNA | |
| SCHEMBL5219235 | 0.85 | KMT2A (0.50) | ALDH1A1HPGDNPC1LMNAHTT | |
| SCHEMBL10657225 | 0.85 | HTT (0.53) | ALDH1A1GAALMNAMAPTHTT | |
| SCHEMBL6048079 | 0.85 | KMT2A (0.47) | CTSLALDH1A1HPGDGAALMNA | |
| SCHEMBL18803708 | 0.83 | ALDH1A1 (0.55) | CTSLALDH1A1HPGDNPC1LMNA | |
| SCHEMBL7923262 | 0.82 | TP53 (0.45) | ALDH1A1HPGDGAALMNASMN1; SMN2 | |
| SCHEMBL16447466 | 0.77 | FOLH1 (0.54) | CTSLALDH1A1HPGDNPC1CA2 | |
| SCHEMBL19612083 | 0.77 | FOLH1 (0.54) | CTSLALDH1A1HPGDNPC1CA2 | |
| SCHEMBL4678063 | 0.77 | LMNA (0.49) | ALDH1A1NPC1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |