Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501206 | 0.81 | KCNH2 (0.31) | KCNH2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6506684 | 0.72 | CSNK2A1 (0.32) | KCNH2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6509717 | 0.72 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL6501642 | 0.65 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL6508275 | 0.65 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL6501496 | 0.63 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL6530621 | 0.63 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL6502365 | 0.61 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL6508139 | 0.61 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL1628646 | 0.61 | PIM3 (0.42) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |