Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.30 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.30 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509717 | 0.91 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL6506826 | 0.81 | KCNH2 (0.35) | KCNH2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL6506684 | 0.77 | CSNK2A1 (0.32) | KCNH2CSNK2A1CSNK2A2CSNK2BPIM1 | |
| SCHEMBL6507753 | 0.75 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL6509190 | 0.72 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL6503701 | 0.70 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL6501496 | 0.68 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL8113361 | 0.62 | KDM4E (0.40) | KCNH2MAPKAPK3 | |
| SCHEMBL1628321 | 0.62 | KCNH2 (0.38) | KCNH2CSNK2A1PIM1CDK2FLT4 | |
| SCHEMBL6670523 | 0.61 | LMNA (0.53) | KCNH2CSNK2A1CSNK2A2CSNK2BMAPKAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |