Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.49 |
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380133 | 0.85 | PPARA (0.55) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6496654 | 0.84 | PPARA (0.47) | PPARAPPARGMRGPRX4LMNASMN1; SMN2 | |
| SCHEMBL6779971 | 0.82 | LMNA (0.56) | LMNASMN1; SMN2 | |
| SCHEMBL14398158 | 0.79 | PPARA (0.69) | PPARAPPARGMRGPRX4SMN1; SMN2 | |
| SCHEMBL6494445 | 0.77 | CYP4F2 (0.54) | PPARAPPARGMRGPRX4LMNASMN1; SMN2 | |
| SCHEMBL11731466 | 0.77 | PPARA (0.79) | PPARAPPARG | |
| SCHEMBL31006902 | 0.76 | PPARA (0.57) | PPARAPPARGMRGPRX4LPAR1 | |
| SCHEMBL20522235 | 0.76 | PPARA (0.57) | PPARAPPARGMRGPRX4LPAR1 | |
| SCHEMBL6496640 | 0.76 | LDHA (0.48) | PPARAPPARGPPARDMRGPRX4PSEN1 | |
| SCHEMBL20522149 | 0.76 | PPARG (0.60) | PPARAPPARGMRGPRX4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |