Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504864 | 0.85 | MMP8 (0.63) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL15669148 | 0.85 | L3MBTL1 (0.56) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL3994508 | 0.84 | L3MBTL1 (0.55) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL5992353 | 0.81 | L3MBTL1 (0.53) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL6036021 | 0.81 | L3MBTL1 (0.58) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL2807182 | 0.81 | PPARG (0.55) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL14176244 | 0.80 | LMNA (0.54) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL14210007 | 0.79 | ALDH1A1 (0.53) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL6716118 | 0.79 | L3MBTL1 (0.53) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 | |
| SCHEMBL6713228 | 0.79 | PPARG (0.53) | NR1H4L3MBTL1LMNAALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016911-A1 | 4-PYRIMIDONE DERIVATIVES AND THEIR USE AS PEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-02-24 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |