Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531527 | 0.84 | HDAC1 (0.50) | GAA | |
| SCHEMBL6513490 | 0.79 | TSHR (0.48) | TSHRKCNH2MAOBLTA4H | |
| SCHEMBL6513481 | 0.66 | TSHR (0.56) | TSHRKCNH2MAOBLTA4H | |
| SCHEMBL22831362 | 0.66 | KCNH2 (0.67) | TSHRKCNH2LTA4H | |
| SCHEMBL17682060 | 0.65 | TSHR (0.81) | TSHRKCNH2MAOBLTA4H | |
| SCHEMBL6529349 | 0.63 | HDAC1 (0.66) | — | |
| SCHEMBL6510292 | 0.63 | HDAC1 (0.59) | — | |
| SCHEMBL6509841 | 0.63 | HDAC1 (0.46) | TSHR | |
| SCHEMBL12225915 | 0.62 | CHRNB2 (0.67) | TSHRKCNH2LTA4H | |
| SCHEMBL4775058 | 0.61 | KCNH2 (0.79) | TSHRKCNH2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |