Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lindane SCHEMBL9209782 | 0.97 | — | — | |
| SCHEMBL2462816 | 0.85 | — | — | |
| Hexane SCHEMBL3624927 | 0.74 | TSHR (0.39) | — | |
| Lindane SCHEMBL3809125 | 0.69 | LMNA (0.36) | — | |
| Lindane SCHEMBL9815928 | 0.69 | LMNA (0.36) | — | |
| Lindane SCHEMBL10767699 | 0.67 | LMNA (0.33) | — | |
| SCHEMBL30423540 | 0.63 | — | — | |
| Lindane SCHEMBL8470986 | 0.61 | — | — | |
| Lindane SCHEMBL5667613 | 0.61 | — | — | |
| Lindane SCHEMBL9845655 | 0.60 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |
| EP-1416798-A2 | THIAZOLO 4,5-b]PYRIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2004029179-A1 | PROCESS AND CATALYSTS FOR DEEP DESULPHURIZATION OF FUELS | ENI S.P.A. (IT) | 2004-04-08 | — | — | WO | disclosed |
| EP-1352014-A2 | MIXING | Dow Corning Corporation (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2003006470-A2 | THIAZOLO [4,5-b]PYRIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-23 | — | — | WO | disclosed |
| WO-2002044247-A2 | PROCESS FOR PREPARING SILOXANE-FILLER COMPOSITIONS USING AN EXTRUDER MIXER | DOW CORNING CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-1037946-A1 | ADDITION CROSS-LINKING SILICONE RUBBER MIXTURES, A METHOD FOR THEIR PRODUCTION AND THEIR USE | GE Bayer Silicones GmbH & Co. KG (DE) | 2000-09-27 | — | — | EP | disclosed |
| WO-2000022047-A1 | ADDITION CROSS-LINKING SILICONE RUBBER MIXTURES, A METHOD FOR THEIR PRODUCTION AND THEIR USE | GE BAYER SILICONES GMBH & CO. KG (DE) | 2000-04-20 | — | — | WO | disclosed |
| EP-0792195-A4 | NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS | COMPLEX FLUID SYSTEMS INC (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0915700-A1 | USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS | MOLECUMETICS, LTD. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1996012716-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP. (KR) | 1996-05-02 | — | — | WO | disclosed |
| EP-0515535-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1996-01-17 | — | — | EP | disclosed |
| EP-0665868-A1 | AQUEOUS BINDERS AND COATING AGENTS. | WACKER CHEMIE GMBH (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994009075-A1 | AQUEOUS BINDERS AND COATING AGENTS | WACKER-CHEMIE GMBH (DE) | 1994-04-28 | — | — | WO | disclosed |
| EP-0507883-A4 | THIN-FILM SPECTROSCOPIC SENSOR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0507883-A1 | THIN-FILM SPECTROSCOPIC SENSOR | BATTELLE DEVELOPMENT CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0470995-A1 | USE OF STEROIDAL COMPOUNDS AS ANTI-FUNGAL AGENTS. | NAT RES DEV (GB) | 1992-02-19 | — | — | EP | disclosed |
| WO-1991010122-A1 | THIN-FILM SPECTROSCOPIC SENSOR | BATTELLE DEVELOPMENT CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |
| WO-1991006661-A1 | LIPASE-CATALYZED IN SITU GENERATION OF MONO- AND DI-GLYCERIDES | OPTA FOOD INGREDIENTS, INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| EP-0310320-A2 | Curable composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |