Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061963 | 0.87 | KDM1A (0.42) | RHEBMAPK10DGAT1KCNH2AMY1A | |
| SCHEMBL6513301 | 0.86 | RHEB (0.44) | RHEBMAPK10DGAT1SOAT1KCNH2 | |
| SCHEMBL10765326 | 0.84 | MAPK10 (0.42) | RHEBMAPK10AMY1APKN1PKN2 | |
| SCHEMBL10764183 | 0.82 | MAPK10 (0.41) | RHEBMAPK10AMY1ACHEK2PKN1 | |
| SCHEMBL10765448 | 0.82 | ATR (0.44) | MAPK10AMY1AF7 | |
| SCHEMBL6061845 | 0.81 | RHEB (0.50) | RHEBDGAT1SOAT1KCNH2AMY1A | |
| SCHEMBL10748660 | 0.79 | CDK4 (0.46) | RHEBMAPK10AMY1APKN1PKN2 | |
| SCHEMBL6061802 | 0.77 | RHEB (0.57) | RHEBDGAT1SOAT1KCNH2CHEK2 | |
| SCHEMBL23540667 | 0.77 | RHEB (0.48) | RHEBDGAT1SOAT1KCNH2CHEK2 | |
| SCHEMBL10760601 | 0.77 | MAPK10 (0.42) | RHEBMAPK10AMY1ACHEK2PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | DDT, DDC, DARS1 | RHEB 412/4885MAPK10 2351/4885DGAT1 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.