Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505960 | 0.91 | RHEB (0.44) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL6508250 | 0.81 | RHEB (0.47) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL6061276 | 0.81 | RHEB (0.49) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL6513301 | 0.80 | RHEB (0.44) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL6061802 | 0.80 | RHEB (0.57) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL23540667 | 0.80 | RHEB (0.48) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL8412123 | 0.80 | RHEB (0.59) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL20982583 | 0.79 | RHEB (0.70) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL8409891 | 0.75 | CHEK2 (0.70) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL3333407 | 0.74 | RHEB (0.68) | RHEBDGAT1SOAT1KCNH2PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682518-A1 | DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | disclosed |
| WO-2005040132-A1 | DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | DDT, DDC, DARS1 | RHEB 412/4885DGAT1 193/4885SOAT1 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.