Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710349 | 0.86 | JAK2 (0.55) | OPRM1BCL9CTNNB1 | |
| SCHEMBL5710353 | 0.79 | JAK2 (0.41) | OPRM1CHRM2CHRM3CCR5BCL9 | |
| SCHEMBL4193616 | 0.75 | OPRM1 (0.70) | OPRM1CHRM2CHRM3CCR5KCNH2 | |
| SCHEMBL4285304 | 0.74 | KMT2A (0.44) | CCR5DPP8DPP7 | |
| SCHEMBL3184871 | 0.74 | OPRM1 (0.47) | OPRM1CHRM2CHRM3CCR5KCNH2 | |
| SCHEMBL3655587 | 0.73 | TSHR (0.47) | — | |
| SCHEMBL5710381 | 0.72 | REN (0.46) | KCNH2 | |
| SCHEMBL3370759 | 0.71 | AGER (0.55) | OPRM1CHRM2CHRM3AGER | |
| SCHEMBL2680993 | 0.71 | CHRM5 (0.43) | OPRM1CHRM2CHRM3 | |
| SCHEMBL27849291 | 0.70 | OPRM1 (0.55) | OPRM1CHRM2CHRM3CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037803-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-04-28 | — | — | WO | disclosed |