Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL3604939 | 0.89 | HTT (0.34) | MAPTMAOAMAOBNPC1HTT | |
| SCHEMBL3590145 | 0.86 | HSP90AA1 (0.39) | MEN1KMT2ACES1PTPRCMAPT | |
| SCHEMBL30200273 | 0.84 | — | — | |
| 2-Aminopyridine SCHEMBL3603239 | 0.83 | NOS3 (0.48) | MEN1KMT2ACES1PTPRCMAPT | |
| SCHEMBL30200347 | 0.79 | GSK3B (0.33) | MEN1KMT2ACDC25BCES1BCHE | |
| SCHEMBL6508302 | 0.74 | PLAU (0.41) | CES1BCHEPOLBKDM4ELMNA | |
| SCHEMBL10846638 | 0.74 | — | — | |
| SCHEMBL14362044 | 0.74 | — | — | |
| SCHEMBL9806078 | 0.69 | TDP2 (0.41) | MEN1KMT2ACDC25BCES1KDM4E | |
| SCHEMBL987746 | 0.69 | TDP2 (0.41) | MEN1KMT2ACDC25BCES1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923263-A | Pharmaceutical composition containing isoquinolinones and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| WO-2024127413-A1 | SOLID STATE FORMS OF ENSIFENTRINE | CIPLA LIMITED (IN) | 2024-06-20 | — | — | WO | claimed |
| US-20230241068-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES | GALAPAGOS NV (BE) | 2023-08-03 | — | — | US | claimed |
| CN-114280200-B | Method for simultaneously detecting three component contents of praziquantel, clofenacin and milbexime | 上海汉维生物医药科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| EP-4186507-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES | Galapagos N.V. (BE) | 2023-05-31 | — | — | EP | claimed |
| CN-114280200-A | Method for simultaneously detecting content of three components of praziquantel, clofenacin and milbemycin oxime | 上海汉维生物医药科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| EP-3710004-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES | Galapagos NV (BE) | 2020-09-23 | — | — | EP | claimed |
| EP-3231444-B1 | NEW TREATMENT | VERONA PHARMA PLC (GB) | 2019-12-18 | — | — | EP | claimed |
| EP-1165558-B1 | DERIVATIVES OF PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE | VERNALIS LTD (GB) | 2003-09-24 | — | — | EP | claimed |
| WO-2000078149-A1 | ANTHELMINTIC COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-0242190-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIALS HAVING RHODIUM CYANIDE DOPANTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-04-01 | — | — | EP | claimed |
| US-4925777-A | Direct positives | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-15 | — | — | US | claimed |
| EP-0136847-B1 | PHOTOGRAPHICALLY USEFUL CHALCOGENAZOLYLIDENE AND CHALCOGENAZOLIUM DYES AND METHODS FOR THEIR PREPARATION | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-01-17 | — | — | EP | claimed |
| US-4874866-A | AROMATIC TELLURIUM-NITROGEN COMPOUNDS; DYES | EASTMAN KODAK COMPANY (US) | 1989-10-17 | — | — | US | claimed |
| EP-0138362-B1 | PHOTOGRAPHIC MATERIALS CONTAINING CHALCOGENAZOLES, CHALCOGENAZOLINES AND CHALCOGENAZOLINIUM AND CHALCOGENAZOLIUM SALTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-02-22 | — | — | EP | claimed |
| EP-0242190-A2 | Silver halide photographic materials having rhodium cyanide dopants | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-10-21 | — | — | EP | claimed |
| US-4576905-A | Photographically useful chalcogenazoles, chalcogenazolines, and chalcogenazolinium and chalcogenazolium salts | EASTMAN KODAK COMPANY (US) | 1986-03-18 | — | — | US | claimed |
| US-4575483-A | FACILITATE IMAGE FORMATION | EASTMAN KODAK COMPANY (US) | 1986-03-11 | — | — | US | claimed |
| EP-0138362-A2 | Photographic materials containing chalcogenazoles, chalcogenazolines and chalcogenazolinium and chalcogenazolium salts | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-24 | — | — | EP | claimed |
| EP-0136847-A2 | Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241068-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES | GPR84, GPR65, GPR88 | MEN1 3752/4885KMT2A 4477/4885CDC25B 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.