Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295783 | 0.86 | MAPK14 (0.41) | ALDH1A1MAPTHPGDGFERGSK3B | |
| SCHEMBL2299116 | 0.80 | MAPK14 (0.42) | ALDH1A1MAPTHPGDGSK3BMAPK10 | |
| SCHEMBL2298729 | 0.73 | MAPK14 (0.53) | GSK3BMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4096702 | 0.71 | MAPK14 (0.44) | MEN1NPC1RAB9AKMT2AATM | |
| SCHEMBL6515232 | 0.69 | MAPK14 (0.41) | MAPTGSK3BCCNB2CDK1CCNB1 | |
| SCHEMBL5253575 | 0.62 | MAPK14 (0.45) | MEN1NPC1RAB9AKMT2AATM | |
| SCHEMBL608871 | 0.60 | — | — | |
| SCHEMBL28673160 | 0.60 | CYP2A6 (0.49) | MAPTGSK3AMAPK14ALKCYP3A4 | |
| SCHEMBL6408354 | 0.60 | MAPK10 (0.55) | MEN1NPC1RAB9AKMT2AATM | |
| SCHEMBL27157236 | 0.59 | NPC1 (0.56) | MEN1NPC1RAB9AKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105813-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF CEFTRIAXONE SODIUM | WOCKHARDT LIMITED (IN) | 2005-11-10 | — | — | WO | claimed |
| WO-2005105814-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2005-11-10 | — | — | WO | disclosed |