SCHEMBL6508614

SCHEMBL6508614

C[Si](C)(C)CCOCOCCCCCCOCc1ccc(C[Si](C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
HRH3 Q9Y5N1 3/20 0.31
HRH4 Q9H3N8 2/20 0.31
PLA2G4B P0C869 1/20 0.30
NAAA Q02083 1/20 0.30
FAAH O00519 1/20 0.30
GBA1 P04062 1/20 0.30
UGCG Q16739 1/20 0.30
GBA2 Q9HCG7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6508803 0.82 ESR1 (0.46) ESR1L3MBTL1TDP1GBA1UGCG
SCHEMBL6507918 0.81 ESR1 (0.48) ESR1L3MBTL1TDP1HRH3PLA2G4B
SCHEMBL6506706 0.79 L3MBTL1 (0.61) ESR1L3MBTL1TDP1GBA1UGCG
SCHEMBL6530577 0.76 ESR1 (0.40) ESR1L3MBTL1TDP1HRH3HRH4
SCHEMBL6509740 0.76 ESR1 (0.43) ESR1L3MBTL1TDP1HRH3PLA2G4B
SCHEMBL430043 0.75 ESR1 (0.62) ESR1L3MBTL1TDP1
SCHEMBL6508968 0.73 L3MBTL1 (0.57) ESR1L3MBTL1TDP1HRH3HRH4
SCHEMBL30449856 0.73 IDO1 (0.45) L3MBTL1
SCHEMBL29460875 0.72 TSHR (0.56) L3MBTL1TDP1HRH3HRH4NAAA
SCHEMBL27956696 0.71 TDP1 (0.51) L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005100329-A1 NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME THE UNIVERSITY OF MISSISSIPI (US) 2005-10-27 WO disclosed