Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507568 | 0.84 | RAB9A (0.72) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6507782 | 0.75 | LMNA (0.48) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5923309 | 0.75 | LMNA (0.46) | MEN1KMT2ASMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL6507318 | 0.74 | RAB9A (0.46) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6507381 | 0.74 | RAB9A (0.54) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6511300 | 0.74 | ADORA2A (0.64) | RAB9AKMT2ASMN1; SMN2ADORA2ALMNA | |
| SCHEMBL6510623 | 0.73 | RAB9A (0.67) | RAB9AMEN1KMT2AMAPK1LMNA | |
| SCHEMBL5923041 | 0.72 | SPHK1 (0.44) | MEN1KMT2ASMN1; SMN2MAPK1LMNA | |
| SCHEMBL9737962 | 0.70 | CYP1A2 (0.46) | KMT2ASMN1; SMN2ADORA2ACYP1A2ALDH1A1 | |
| SCHEMBL9622521 | 0.70 | CYP1A2 (0.46) | KMT2ASMN1; SMN2ADORA2ACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |