Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508788 | 0.84 | RAB9A (0.51) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6507381 | 0.84 | RAB9A (0.54) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6514936 | 0.81 | RAB9A (0.74) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6508538 | 0.81 | RAB9A (0.74) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6507782 | 0.80 | LMNA (0.48) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6507318 | 0.79 | RAB9A (0.46) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10501630 | 0.79 | ADORA2A (0.56) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10501633 | 0.79 | ADORA2A (0.56) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6510696 | 0.79 | RAB9A (0.59) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL2801062 | 0.75 | ADORA2A (0.73) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |