Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507985 | 0.84 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6507568 | 0.79 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5923235 | 0.77 | KDM4E (0.39) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6507782 | 0.77 | LMNA (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6514076 | 0.76 | ADORA2A (0.52) | RAB9ANPC1SMN1; SMN2KMT2AADORA2A | |
| SCHEMBL5923382 | 0.75 | MEN1 (0.42) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL6508788 | 0.74 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5923413 | 0.74 | MEN1 (0.39) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6508909 | 0.74 | MAPK1 (0.61) | RAB9ANPC1MAPK1MAPT | |
| SCHEMBL6507381 | 0.70 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |