SCHEMBL6508979

SCHEMBL6508979

COc1cc(C=O)ccc1OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.63
MAPT P10636 10/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
LMNA P02545 4/20 0.53
NPSR1 Q6W5P4 2/20 0.53
HTT P42858 2/20 0.53
ALDH1A1 P00352 11/20 0.51
TSHR P16473 1/20 0.51
HPGD P15428 7/20 0.50
CYP2C9 P11712 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CYP2D6 P10635 1/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
HSP90AA1 P07900 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5973815 0.79 FDPS (1.00) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL9442186 0.78 FDPS (0.90) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL6508984 0.78 ALDH1A1 (0.58) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL2252258 0.77 FDPS (0.81) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL6532147 0.76 FDPS (0.37) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL8719147 0.76 FDPS (0.87) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL9442183 0.76 FDPS (0.87) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL15565921 0.76 FDPS (0.79) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL1414781 0.76 FDPS (0.69) FDPSMAPTSMN1; SMN2LMNANPSR1
SCHEMBL2201517 0.75 FDPS (0.90) FDPSMAPTSMN1; SMN2LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1610176-A2 UV decomposable molecules and a photopatternable monomolecular film formed therefrom SEIKO EPSON CORPORATION (JP) 2005-12-28 EP disclosed