Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509688 | 0.89 | PPARA (0.42) | PPARAPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL3284391 | 0.89 | PPARA (0.38) | PPARAPPARGALDH1A1ADORA3 | |
| SCHEMBL6511112 | 0.88 | PPARA (0.42) | PPARAPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL6511617 | 0.86 | PPARA (0.44) | PPARAPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL6511438 | 0.86 | PPARA (0.60) | PPARAPPARG | |
| SCHEMBL6513058 | 0.86 | PPARA (0.60) | PPARAPPARG | |
| SCHEMBL6512166 | 0.86 | PPARA (0.60) | PPARAPPARG | |
| SCHEMBL6509376 | 0.84 | PPARA (0.42) | PPARAPPARGADORA3 | |
| SCHEMBL3286592 | 0.84 | PPARA (0.41) | PPARAPPARGALDH1A1HTTADORA3 | |
| SCHEMBL3284562 | 0.81 | PPARA (0.34) | PPARAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005047236-A1 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-05-26 | — | — | WO | disclosed |