Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509688 | 0.89 | PPARA (0.42) | PPARAPPARGALDH1A1HTTADORA3 | |
| SCHEMBL6509376 | 0.88 | PPARA (0.42) | PPARAPPARGADORA3 | |
| SCHEMBL3286592 | 0.88 | PPARA (0.41) | PPARAPPARGALDH1A1HTTADORA3 | |
| SCHEMBL6508985 | 0.86 | PPARA (0.40) | PPARAPPARGALDH1A1HTTADORA3 | |
| SCHEMBL6512234 | 0.85 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6511476 | 0.85 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6511449 | 0.85 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6531098 | 0.85 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6511112 | 0.84 | PPARA (0.42) | PPARAPPARGALDH1A1AGTR1AGTR2 | |
| SCHEMBL3284391 | 0.83 | PPARA (0.38) | PPARAPPARGALDH1A1ADORA3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |