Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509688 | 0.90 | PPARA (0.42) | PPARAPPARGADORA3 | |
| SCHEMBL6511617 | 0.88 | PPARA (0.44) | PPARAPPARGADORA3 | |
| SCHEMBL3286592 | 0.85 | PPARA (0.41) | PPARAPPARGADORA3 | |
| SCHEMBL6510857 | 0.85 | PPARA (0.62) | PPARAPPARG | |
| SCHEMBL6509795 | 0.85 | PPARA (0.62) | PPARAPPARG | |
| SCHEMBL6512670 | 0.85 | PPARA (0.62) | PPARAPPARG | |
| SCHEMBL6511563 | 0.85 | PPARA (0.62) | PPARAPPARG | |
| SCHEMBL6510004 | 0.85 | PPARA (0.62) | PPARAPPARG | |
| SCHEMBL6511112 | 0.85 | PPARA (0.42) | PPARAPPARGMEN1KMT2A | |
| SCHEMBL6508985 | 0.84 | PPARA (0.40) | PPARAPPARGADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |