Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528290 | 0.80 | MAPT (0.38) | PTGER4ALDH1A1TSPO | |
| SCHEMBL6507951 | 0.78 | PIM1 (0.52) | POLBTDP1RAB9AHPGD | |
| SCHEMBL6532952 | 0.78 | PIM1 (0.52) | POLBTDP1RAB9AHPGD | |
| SCHEMBL6514234 | 0.77 | LMNA (0.45) | KDM4EALDH1A1TSHRTDP1NPC1 | |
| SCHEMBL17938363 | 0.72 | PTGER4 (0.59) | PTGER4POLBKDM4EALDH1A1TSHR | |
| SCHEMBL6532221 | 0.71 | MTNR1A (0.35) | POLBALDH1A1TSHRNPSR1L3MBTL1 | |
| SCHEMBL8335552 | 0.70 | CYP1A2 (0.56) | POLBKDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL6511729 | 0.70 | MEN1 (0.39) | POLBKDM4EALDH1A1TSHRCYP1A2 | |
| SCHEMBL11829790 | 0.69 | PTGER4 (0.72) | PTGER4POLBKDM4EALDH1A1ATM | |
| SCHEMBL1816905 | 0.68 | ALDH1A1 (0.59) | ALDH1A1ATML3MBTL1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |