Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361670 | 0.86 | FABP3 (0.51) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL31653573 | 0.83 | FABP4 (0.46) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL9765827 | 0.83 | MAPT (0.49) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL529977 | 0.83 | FABP4 (0.46) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL28932372 | 0.82 | FABP3 (0.45) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL529975 | 0.80 | FABP3 (0.49) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL2362774 | 0.80 | FABP3 (0.58) | FABP3FABP4FABP5BCAT2HPGD | |
| SCHEMBL5582520 | 0.78 | HK2 (0.48) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL5479516 | 0.77 | FABP3 (0.41) | MKNK1MKNK2FABP3FABP4FABP5 | |
| SCHEMBL5517158 | 0.77 | FABP3 (0.46) | MKNK1MKNK2FABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042496-A1 | (BENZIMIDAZOL-2-YL)-PHENYL-BENZYL-AMINE DERIVATIVES AND METHODS FOR INHIBITING HEPARANASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |