Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31653573 | 1.00 | FABP4 (0.46) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL529975 | 0.88 | FABP3 (0.49) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL23361670 | 0.87 | FABP3 (0.51) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL9765827 | 0.84 | MAPT (0.49) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL20552421 | 0.83 | BCAT2 (0.50) | FABP4MKNK1MKNK2BCAT2KDM4E | |
| SCHEMBL6509108 | 0.83 | MKNK1 (0.47) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL28932372 | 0.83 | FABP3 (0.45) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL2362774 | 0.81 | FABP3 (0.58) | FABP4FABP3FABP5BCAT2HTT | |
| SCHEMBL531530 | 0.81 | IKBKB (0.49) | FABP4FABP3FABP5MKNK1MKNK2 | |
| SCHEMBL5582520 | 0.79 | HK2 (0.48) | FABP4FABP3FABP5MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |