SCHEMBL9765827

SCHEMBL9765827

COc1ccc(C(N)=O)c(-c2ccccc2)c1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
IKBKB O14920 1/20 0.46
FABP3 P05413 1/20 0.46
FABP4 P15090 1/20 0.46
FABP5 Q01469 1/20 0.46
PDE4A P27815 2/20 0.45
PDE4B Q07343 2/20 0.45
PDE4C Q08493 2/20 0.45
PDE4D Q08499 2/20 0.45
MKNK1 Q9BUB5 1/20 0.45
MKNK2 Q9HBH9 1/20 0.45
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GAA P10253 2/20 0.42
CHEK1 O14757 1/20 0.42
BCAT2 O15382 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7273539 0.87 MAPT (0.60) MAPTTDP1FABP3FABP4FABP5
SCHEMBL23361670 0.87 FABP3 (0.51) MAPTTDP1IKBKBFABP3FABP4
SCHEMBL27414108 0.86 MAPT (0.50) MAPTTDP1FABP3FABP4FABP5
SCHEMBL529977 0.84 FABP4 (0.46) MAPTIKBKBFABP3FABP4FABP5
SCHEMBL31653573 0.84 FABP4 (0.46) MAPTIKBKBFABP3FABP4FABP5
SCHEMBL28932372 0.83 FABP3 (0.45) MAPTIKBKBFABP3FABP4FABP5
SCHEMBL6509108 0.83 MKNK1 (0.47) MAPTIKBKBFABP3FABP4FABP5
SCHEMBL8799008 0.82 MAPT (0.47) MAPTTDP1FABP3FABP4FABP5
SCHEMBL14052472 0.82 SMN1; SMN2 (0.47) MAPTTDP1FABP3FABP4FABP5
SCHEMBL28418609 0.82 MAPT (0.46) MAPTTDP1FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460083-A1 DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION. ROTTA RESEARCH LAB (IT) 1991-12-11 EP disclosed