Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509978 | 0.88 | NOS3 (0.48) | NOS3NOS1NOS2RXFP1ALDH1A1 | |
| SCHEMBL6510782 | 0.81 | NOS3 (0.45) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL6513366 | 0.81 | ALDH1A1 (0.53) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL6513314 | 0.80 | ALDH1A1 (0.47) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL6518218 | 0.78 | RECQL (0.51) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL2803592 | 0.78 | KMT2A (0.51) | NOS3NOS1RXFP1ALDH1A1LMNA | |
| SCHEMBL6515597 | 0.78 | NOS3 (0.45) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL5923038 | 0.77 | POLB (0.42) | RXFP1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL6155618 | 0.76 | SIGMAR1 (0.54) | NOS3NOS1NOS2LMNAGRIN2D | |
| SCHEMBL8742419 | 0.75 | NOS3 (0.58) | NOS3NOS1NOS2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |