SCHEMBL6509262

SCHEMBL6509262

CNC1SCN(c2ccc(F)c(Br)c2)C1=O

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 10/20 0.36
KCNJ11 Q14654 10/20 0.36
ABCC8 Q09428 9/20 0.36
KCNJ8 Q15842 9/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 3/20 0.34
NPSR1 Q6W5P4 2/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
RECQL P46063 1/20 0.33
CACNA1B Q00975 1/20 0.33
BPTF Q12830 1/20 0.32
MCHR1 Q99705 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510492 0.84 KAT2B (0.46) L3MBTL1LMNAMEN1KMT2ARECQL
SCHEMBL6511176 0.82 AR (0.50)
SCHEMBL6512004 0.73 NOTUM (0.46) MEN1KMT2A
SCHEMBL6508550 0.72 CA12 (0.43) TSHRMEN1KMT2A
SCHEMBL6507979 0.70 DRD2 (0.43) MCHR1
SCHEMBL8089006 0.68 TSHR (0.36) ABCC9KCNJ11ABCC8KCNJ8L3MBTL1
SCHEMBL8606629 0.68 MCHR1 (0.41) L3MBTL1TSHRMCHR1
SCHEMBL8604544 0.68 HDAC6 (0.42) MCHR1
SCHEMBL8089969 0.67 NOTUM (0.38) L3MBTL1LMNAMEN1KMT2AMCHR1
SCHEMBL8090534 0.67 KAT2B (0.48) L3MBTL1LMNAMEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005000824-A1 LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 WO disclosed