Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 9/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 9/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 9/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 9/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819041 | 0.84 | CYP1A2 (0.44) | IDO1L3MBTL1TDO2 | |
| SCHEMBL8089959 | 0.82 | RAD51 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL8606629 | 0.77 | MCHR1 (0.41) | TSHRIDO1L3MBTL1MCHR1 | |
| SCHEMBL8082052 | 0.76 | SLC6A2 (0.45) | — | |
| SCHEMBL8090197 | 0.74 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL8089008 | 0.73 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL8666490 | 0.68 | KMT2A (0.35) | — | |
| SCHEMBL12445149 | 0.68 | ALDH1A1 (0.49) | TSHRIDO1 | |
| SCHEMBL6509262 | 0.68 | ABCC9 (0.36) | TSHRABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8666484 | 0.67 | GRM2 (0.41) | MCHR1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022976-A | Process for the production of 5-hydroxyoxazolidinones | ZENECA LIMITED | 2000-02-08 | — | — | US | disclosed |
| EP-0880510-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028138-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |