Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516317 | 0.89 | FFAR4 (0.39) | HSP90AA1HPGDALDH1A1AKR1B1PTGDR2 | |
| SCHEMBL6511874 | 0.88 | AKR1B1 (0.43) | HSP90AA1HPGDALDH1A1AKR1B1PTGDR2 | |
| SCHEMBL6510768 | 0.87 | ALDH1A1 (0.43) | HSP90AA1HPGDALDH1A1THRATHRB | |
| SCHEMBL6508797 | 0.87 | ALDH1A1 (0.42) | HSP90AA1HPGDALDH1A1PTGDR2THRA | |
| SCHEMBL6509305 | 0.83 | ALDH1A1 (0.38) | HSP90AA1HPGDALDH1A1THRATHRB | |
| SCHEMBL6509513 | 0.83 | SLC6A9 (0.41) | HPGDALDH1A1L3MBTL1MEP1BEGFR | |
| SCHEMBL6510314 | 0.83 | HPGD (0.40) | HSP90AA1HPGDPRMT1AKR1B1PTGDR2 | |
| SCHEMBL6510665 | 0.82 | MEP1B (0.39) | HSP90AA1HPGDALDH1A1THRATHRB | |
| SCHEMBL6515036 | 0.82 | HPGD (0.41) | HPGDPRMT1ALDH1A1L3MBTL1MEP1B | |
| SCHEMBL6511963 | 0.81 | MEP1B (0.47) | MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |