Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788058 | 0.78 | — | — | |
| SCHEMBL375913 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL9788022 | 0.78 | GALR2 (0.33) | MAPTALDH1A1GALR2HPGDMPI | |
| SCHEMBL9788009 | 0.78 | GPR35 (0.31) | — | |
| SCHEMBL17304299 | 0.78 | HTT (0.39) | MAPTALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL9788041 | 0.78 | GALR2 (0.33) | MAPTALDH1A1GALR2HPGDMPI | |
| SCHEMBL9788008 | 0.78 | MAPT (0.32) | MAPT | |
| SCHEMBL9788026 | 0.74 | NPC1 (0.36) | MAPTALDH1A1GALR2HTTSMN1; SMN2 | |
| SCHEMBL9788027 | 0.74 | F2RL3 (0.34) | MAPTHPGDMPIHTTNPSR1 | |
| SCHEMBL9788010 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698357-A | 2,4-dichloro-5-nitro-thiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | claimed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-02-23 | — | — | US | disclosed |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-02-23 | — | — | US | disclosed |
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |
| US-5075326-A | Fungicides, microbiocides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |
| US-5071865-A | Fungicides, bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| EP-0402716-A1 | 2-Acylamino-4-halogeno-5-nitrothiazole derivatives, process for their preparation, their use in pesticides and new intermediate products | BAYER AG (DE) | 1990-12-19 | — | — | EP | disclosed |
| US-4962102-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| EP-0351662-A3 | 4-HALO-5-NITROTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS PESTICIDES, AND INTERMEDIATES | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |
| EP-0351662-A2 | 4-Halo-5-nitrothiazole derivatives, process for their preparation, their use as pesticides, and intermediates | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0351662-A2 | 4-Halo-5-nitrothiazole derivatives, process for their preparation, their use as pesticides, and intermediates | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |
| US-4698357-A | 2,4-dichloro-5-nitro-thiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| US-4698357-A | 2,4-dichloro-5-nitro-thiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| US-4698357-A | 2,4-dichloro-5-nitro-thiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | MAPT 3010/4885ALDH1A1 1427/4885GALR2 4151/4885 |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | MAPT 3010/4885ALDH1A1 1427/4885GALR2 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.