SCHEMBL9788008

SCHEMBL9788008

O=[N+]([O-])c1sc(Cl)nc1I

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9788055 0.78 GALR2 (0.34) MAPT
SCHEMBL6509690 0.78 MAPT (0.31) MAPT
SCHEMBL9788041 0.75 GALR2 (0.33) MAPT
SCHEMBL9788022 0.71 GALR2 (0.33) MAPT
SCHEMBL9788052 0.67
SCHEMBL9789011 0.66 KMT2A (0.50) MAPT
SCHEMBL9469213 0.65 KDM4E (0.34) MAPT
SCHEMBL9788009 0.62 GPR35 (0.31)
SCHEMBL375913 0.62 ALDH1A1 (0.42) MAPT
SCHEMBL17304299 0.62 HTT (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075326-A Fungicides, microbiocides BAYER AKTIENGESELLSCHAFT (DE) 1991-12-24 US disclosed
US-5071865-A Fungicides, bactericides BAYER AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
EP-0402716-A1 2-Acylamino-4-halogeno-5-nitrothiazole derivatives, process for their preparation, their use in pesticides and new intermediate products BAYER AG (DE) 1990-12-19 EP disclosed
US-4962102-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US disclosed
EP-0351662-A2 4-Halo-5-nitrothiazole derivatives, process for their preparation, their use as pesticides, and intermediates BAYER AG (DE) 1990-01-24 EP disclosed