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Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6509718

O=C(CCCS)NCCN(CCNC(=O)C[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)CCNC(=O)C[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O.S.S

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 6/20 0.36
▸ SELP P16109 4/20 0.36
▸ EPHX2 P34913 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ MMP13 P45452 1/20 0.34
▸ HDAC3 O15379 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ DNM1 Q05193 1/20 0.33
▸ SLC5A1 P13866 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509715 0.91 PYGB (0.33) PYGBSELPEPHX2GAAMMP13
Hydrogen Sulfide SCHEMBL4468953 0.83 PYGB (0.40) PYGBSELPGAA
SCHEMBL6515145 0.79 DNM1 (0.35) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL6515149 0.79 DNM1 (0.35) HDAC3HDAC1HDAC2HDAC8HDAC6
Hydrogen Sulfide SCHEMBL6886073 0.76 PYGB (0.47) PYGBSELPGAA
Hydrochloric Acid SCHEMBL2536717 0.74 DNM1 (0.49) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL20161703 0.72 PYGB (0.51) PYGBSELPGAA
SCHEMBL17962617 0.72 EPHX2 (0.40) PYGBSELPEPHX2GAA
SCHEMBL20161560 0.70 NAAA (0.47) PYGBEPHX2GAA
SCHEMBL20161323 0.70 NAAA (0.47) PYGBEPHX2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050272670-A1 Synthesis and use of glycodendrimer reagents DAVIS BENJAMIN G 2005-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050272670-A1 Synthesis and use of glycodendrimer reagents STT3A, PTMS, STT3B PYGB 1271/4885SELP 651/4885EPHX2 2461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.