Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508430 | 0.93 | CNR1 (0.44) | CNR1AVPR2AVPR1AHTTADORA2A | |
| SCHEMBL6514331 | 0.92 | CNR1 (0.42) | CNR1AVPR2AVPR1AHTTADORA2A | |
| SCHEMBL6510956 | 0.88 | CNR1 (0.42) | CNR1AVPR2AVPR1AADORA2AADORA2B | |
| SCHEMBL6509571 | 0.86 | PIK3CA (0.44) | CNR1AVPR1AADORA2AADORA2BADORA1 | |
| SCHEMBL6512878 | 0.84 | TRPA1 (0.42) | CNR1AVPR2AVPR1AADORA2AADORA2B | |
| SCHEMBL6506306 | 0.84 | CNR1 (0.39) | CNR1AVPR2AVPR1AADORA2AADORA2B | |
| SCHEMBL6517585 | 0.84 | CNR1 (0.43) | CNR1AVPR2AVPR1A | |
| SCHEMBL6513768 | 0.83 | CNR1 (0.38) | CNR1AVPR2AVPR1A | |
| SCHEMBL6510280 | 0.82 | CNR1 (0.38) | CNR1 | |
| SCHEMBL6507869 | 0.80 | CNR1 (0.49) | CNR1AVPR2AVPR1AADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049615-A1 | PYRAZOLO`1,5-A!`1,3,5! TRIAZIN -4-ONE DERIVATIVES AS CB1 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-06-02 | — | — | WO | claimed |
| WO-2005049615-A1 | PYRAZOLO`1,5-A!`1,3,5! TRIAZIN -4-ONE DERIVATIVES AS CB1 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-06-02 | — | — | WO | disclosed |