SCHEMBL6509895

SCHEMBL6509895

COc1ccc(N(c2ccccc2)c2ccc(CO)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.52
CNR1 P21554 2/20 0.46
CNR2 P34972 2/20 0.46
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
ACHE P22303 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
SIGMAR1 Q99720 1/20 0.44
TSHR P16473 1/20 0.43
CA4 P22748 1/20 0.43
USP2 O75604 1/20 0.43
TP53 P04637 1/20 0.43
RNF4 P78317 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19270226 1.00 LTA4H (0.52) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL18268266 1.00 LTA4H (0.52) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL15179039 0.95 LTA4H (0.47) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL13777888 0.95 LTA4H (0.47) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL10065633 0.95 LTA4H (0.47) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL19270250 0.95 LTA4H (0.47) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL18268265 0.94 LTA4H (0.46) LTA4HCNR1CNR2MTNR1AMTNR1B
SCHEMBL12732320 0.93 IDO1 (0.47) LTA4HTSHRTP53
SCHEMBL10062238 0.93 IDO1 (0.47) LTA4HTSHRTP53
SCHEMBL3929503 0.93 IDO1 (0.47) LTA4HTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703373-B2 Electrophotographic photoreceptor, method of producing electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-04-22 US disclosed
US-20130065169-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2013-03-14 US disclosed
US-20110200926-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-08-18 US disclosed
US-20110081607-A1 METHYLOL COMPOUND, ALDEHYDE COMPOUND, METHOD FOR PREPARING THE METHYLOL COMPOUND USING THE ALDEHYDE COMPOUND, AND PHOTORECEPTOR USING THE METHYLOL COMPOUND RICOH COMPANY, LTD., (JP) 2011-04-07 US disclosed
US-7700248-B2 Organic charge transporting polymers including charge transport moieties and silane groups, and silsesquioxane compositions prepared therefrom EASTMAN KODAK COMPANY (US) 2010-04-20 US disclosed
US-7393415-B2 Method and apparatus for applying coating liquid to cylindrical substrate and method for producing electrophotographic photoreceptor and electrophotographic photoreceptor produced by the production method SHARP KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-6878468-B2 Compounds capable of transporting/injecting hole and organic electroluminescent device having self-assembled monolayer comprising the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2005-04-12 US disclosed
US-20030087127-A1 Compounds capable of transporting/injecting hole and organic electroluminescent device having self-assembled monolayer comprising the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2003-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087127-A1 Compounds capable of transporting/injecting hole and organic electroluminescent device having self-assembled monolayer comprising the same SLCO4C1, SLC26A3, SLCO2B1 LTA4H 1196/4885CNR1 1711/4885CNR2 2280/4885
US-20110081607-A1 METHYLOL COMPOUND, ALDEHYDE COMPOUND, METHOD FOR PREPARING THE METHYLOL COMPOUND USING THE ALDEHYDE COMPOUND, AND PHOTORECEPTOR USING THE METHYLOL COMPOUND ALDH1A2, MGMT, MCOLN2 LTA4H 760/4885CNR1 2555/4885CNR2 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.