Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15252995 | 0.81 | ALDH1A1 (0.40) | PTGS1PTGS2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7443645 | 0.80 | ALDH1A1 (0.38) | ALDH1A1PKMPTPN1 | |
| SCHEMBL92947 | 0.79 | CA2 (0.33) | PTGS1PTGS2MGLLFAAHKMT2A | |
| SCHEMBL43970 | 0.78 | PTPN1 (0.42) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL12094816 | 0.78 | MGLL (0.39) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL15253083 | 0.77 | KMT2A (0.40) | PTGS1PTGS2KMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4277446 | 0.76 | PTPN1 (0.41) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL2219783 | 0.76 | CA2 (0.43) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL2034675 | 0.76 | MGLL (0.38) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL12275897 | 0.74 | SMN1; SMN2 (0.36) | PTGS1PTGS2MGLLFAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936298-B2 | Antithrombogenic membrane mimetic compositions and methods | EMORY UNIVERSITY (US) | 2005-08-30 | — | — | US | disclosed |
| US-20040073295-A1 | Antithrombogenic membrane mimetic compositions and methods | EMORY UNIVERSTIY | 2004-04-15 | — | — | US | disclosed |
| US-6720161-B1 | SUBSTRATE IS COVALENTLY BOUND TO A MONOMERIC OR OLIGOMERIC CONSTITUTIONAL UNIT OF A GEL AND THE RESULTANT PRODUCT IS POLYMERIZED. | GESELLSCHAFT FUER BIOTECHNOLOGISCHE FORSCHUNG MBH (DE) | 2004-04-13 | — | — | US | disclosed |
| EP-1272237-A1 | ANTITHROMBOGENIC MEMBRANE MIMETIC COMPOSITIONS AND METHODS | Emory University (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001078800-A1 | ANTITHROMBOGENIC MEMBRANE MIMETIC COMPOSITIONS AND METHODS | EMORY UNIVERSITY (US) | 2001-10-25 | — | — | WO | disclosed |