SCHEMBL6509941

SCHEMBL6509941

CCc1cc(Br)ccc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.45
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 2/20 0.41
PTPRC P08575 1/20 0.41
FBP1 P09467 1/20 0.40
DPP4 P27487 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
KMT2A Q03164 1/20 0.38
PRNP P04156 1/20 0.38
PPARG P37231 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
NR2E3 Q9Y5X4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyoxylate SCHEMBL7968382 0.89 PTGDR2 (0.44) PTGDR2ALDH1A1FBP1HTTMMP2
SCHEMBL17787534 0.88 S100A4 (0.40) PTGDR2ALDH1A1MAPK1PTPRCHPGD
SCHEMBL6517710 0.85 PTGDR2 (0.40) PTGDR2ALDH1A1MAPK1PTPRCDPP4
SCHEMBL12798321 0.83 S100A4 (0.46) PTGDR2ALDH1A1MAPK1PTPRCHPGD
SCHEMBL14825943 0.83 ALDH1A1 (0.43) ALDH1A1HPGDKMT2ARXFP1S100A4
SCHEMBL1988581 0.82 PTGDR2 (0.46) PTGDR2ALDH1A1MAPK1PTPRCDPP4
SCHEMBL17063605 0.81 ESR1 (0.44) ALDH1A1HTTKMT2AS100A4
SCHEMBL18311447 0.81 S100A4 (0.35) PTGDR2ALDH1A1MAPK1PTPRCHPGD
SCHEMBL8780418 0.81 LIPG (0.40) PPARG
SCHEMBL3171483 0.81 DPP4 (0.59) PTGDR2ALDH1A1MAPK1PTPRCDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517905-B Synthesis method of trans-4- (4-alkenyl cyclohexyl) -1,1' -biphenyl compound 西安瑞联新材料股份有限公司 2022-08-02 CN disclosed
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed