SCHEMBL6509952

SCHEMBL6509952

C#Cc1ccc(-c2ccccc2C#C)cc1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.36
BACE1 P56817 2/20 0.35
ESR2 Q92731 1/20 0.34
PTPN1 P18031 1/20 0.34
PTPN6 P29350 1/20 0.34
PTPN11 Q06124 1/20 0.34
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KLKB1 P03952 1/20 0.33
TRPA1 O75762 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510422 0.83 BACE1 (0.36) BACE1PTPN1PTPN6PTPN11ALOX5AP
SCHEMBL29588993 0.79 CYP3A4 (0.44) ESR2ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL30607044 0.78 ESR2 (0.38) ARESR2TRPA1APP
SCHEMBL29051242 0.78 ESR2 (0.38) ARESR2TRPA1APP
SCHEMBL19590795 0.77 ALOX5AP (0.39) BACE1ALOX5APFEN1KLKB1
SCHEMBL28818238 0.76 ALDH1A1 (0.45) PTPN1PTPN6PTPN11ALDH1A1HSD17B10
SCHEMBL29159006 0.76 CYP2A6 (0.46) BACE1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL6757877 0.74 CYP2A6 (0.44) BACE1ESR2ALDH1A1HSD17B10L3MBTL1
SCHEMBL1302811 0.73 CYP2A6 (0.48) BACE1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL6509956 0.73 MEN1 (0.39) PTPN1PTPN6PTPN11ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed