Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfinalol SCHEMBL78008 | 0.90 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL6510272 | 0.90 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL29387627 | 0.90 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL29918144 | 0.89 | ADRA1A (0.65) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL121669 | 0.89 | ADRA1A (0.65) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL1650838 | 0.88 | SLC6A4 (0.64) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL9548053 | 0.81 | SLC6A4 (0.60) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11193698 | 0.79 | SLC6A4 (0.53) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL8855337 | 0.78 | ADRB2 (0.82) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11153294 | 0.77 | ADRB2 (0.64) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198587-A | Adrenergic Blocking Agents, Hypotensive Agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| US-5063246-A | Hypotensive | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| US-4880841-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |