Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638787 | 0.84 | MAPT (0.53) | HPGDGAANPC1RAB9ALMNA | |
| SCHEMBL10510071 | 0.81 | CYP1A2 (0.38) | HPGDALDH1A1KDM4EGAAMAPK14 | |
| SCHEMBL29410994 | 0.81 | NPC1 (0.54) | HPGDNPC1RAB9AHDAC6HDAC1 | |
| SCHEMBL7160197 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL31571984 | 0.77 | HPGD (0.62) | HPGDALDH1A1KDM4EGAARAB9A | |
| SCHEMBL22276770 | 0.76 | HPGD (0.49) | HPGDALDH1A1KDM4EGAAMAPK14 | |
| SCHEMBL13732067 | 0.76 | NPSR1 (0.55) | ALDH1A1KDM4ENPC1RAB9APOLB | |
| SCHEMBL22722623 | 0.76 | BRD4 (0.69) | KMT2A | |
| SCHEMBL6351854 | 0.75 | MAPT (0.45) | HPGDALDH1A1KDM4EGAANPC1 | |
| SCHEMBL166484 | 0.73 | LMNA (0.82) | HPGDALDH1A1KDM4EGAAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019182-A1 | PYRAZOLYLMETHYLBENZAMIDE DERIVATIVES AS P2XT-RECEPTOR ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | claimed |
| CN-106470962-A | The combination of new nitrification and biological pesticide and the combination of (thio) phosphoric triamides and biological pesticide | 巴斯夫欧洲公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106232557-A | Novel nitrification inhibitors | 巴斯夫欧洲公司 | 2016-12-14 | — | — | CN | disclosed |
| WO-2010115264-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | WO | disclosed |
| WO-2005019182-A1 | PYRAZOLYLMETHYLBENZAMIDE DERIVATIVES AS P2XT-RECEPTOR ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005019182-A1 | PYRAZOLYLMETHYLBENZAMIDE DERIVATIVES AS P2XT-RECEPTOR ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |
| US-4752321-A | Benzoylaminomethylpyrazoles and -furans, composition containing them, and fungicidal and plant growth regulating method of using them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-06-21 | — | — | US | disclosed |
| US-4728665-A | SYSTEMIC | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-01 | — | — | US | disclosed |