Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410994 | 0.90 | NPC1 (0.54) | SMN1; SMN2RAB9ANPC1PRSS1CTSG | |
| SCHEMBL6510429 | 0.84 | HPGD (0.51) | SMN1; SMN2RAB9ANPC1PRSS1CTSG | |
| SCHEMBL9229356 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL22722613 | 0.77 | BRD4 (0.66) | MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7160197 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2GAA | |
| SCHEMBL483578 | 0.75 | RAB9A (0.74) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL1300262 | 0.75 | MAPT (0.52) | MAPTSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL3192014 | 0.74 | LMNA (0.77) | SMN1; SMN2RAB9ANPC1PRSS1CTSG | |
| SCHEMBL751214 | 0.73 | HDAC2 (0.80) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL669816 | 0.73 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885970-A1 | Fungicide compositions comprising compound I, at least one succinate dehydrogenase (SDH) inhibitor and at least one triazole fungicide | Bayer CropScience AG (DE) | 2015-06-24 | — | — | EP | disclosed |
| EP-2420142-A1 | Use of N-2-(pyrazolyl)ethylphenylcarboxamides or their salts for controlling powdery mildew primary infections | Bayer CropScience AG (DE) | 2012-02-22 | — | — | EP | disclosed |
| EP-2420142-A1 | Use of N-2-(pyrazolyl)ethylphenylcarboxamides or their salts for controlling powdery mildew primary infections | Bayer CropScience AG (DE) | 2012-02-22 | — | — | EP | disclosed |