Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509334 | 0.90 | PPARA (0.46) | PPARAPPARGS1PR1S1PR3DRD2 | |
| SCHEMBL6510841 | 0.89 | PPARA (0.48) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6508452 | 0.86 | NPC1 (0.44) | PPARAPPARGTHRATHRBBCHE | |
| SCHEMBL6511885 | 0.84 | POLB (0.47) | PPARAPPARG | |
| SCHEMBL6509240 | 0.84 | PPARA (0.41) | PPARAPPARGS1PR1S1PR3DRD2 | |
| SCHEMBL6511867 | 0.83 | HDAC3 (0.47) | PPARAPPARG | |
| SCHEMBL6511699 | 0.83 | FFAR1 (0.43) | PPARAPPARGS1PR1THRB | |
| SCHEMBL6510672 | 0.83 | RAB9A (0.42) | PPARAPPARGS1PR1 | |
| SCHEMBL6511947 | 0.83 | MTNR1A (0.47) | PPARGBCHE | |
| SCHEMBL6531857 | 0.82 | PPARA (0.42) | PPARAPPARGS1PR1S1PR3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |