Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511525 | 0.97 | LTB4R (0.40) | PPARAPPARGLTB4RS1PR1DRD2 | |
| SCHEMBL6512710 | 0.87 | ALDH1A1 (0.43) | LTB4RS1PR1S1PR3S1PR2THRA | |
| SCHEMBL6509334 | 0.87 | PPARA (0.46) | PPARAPPARGS1PR1S1PR3DRD2 | |
| SCHEMBL6510841 | 0.85 | PPARA (0.48) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6511514 | 0.85 | OPRM1 (0.37) | LTB4ROPRM1OPRD1OPRK1FFAR1 | |
| SCHEMBL6512010 | 0.84 | LTB4R (0.42) | LTB4RFFAR1 | |
| SCHEMBL6509203 | 0.84 | PPARA (0.48) | PPARAPPARGS1PR1S1PR3DRD2 | |
| SCHEMBL6508452 | 0.83 | NPC1 (0.44) | PPARAPPARGLTB4RTHRATHRB | |
| SCHEMBL6511885 | 0.81 | POLB (0.47) | PPARAPPARG | |
| SCHEMBL6508460 | 0.81 | HTR2C (0.36) | LTB4RFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |