Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510631 | 0.83 | LMNA (0.33) | LMNA | |
| SCHEMBL6509705 | 0.82 | LMNA (0.32) | LMNA | |
| SCHEMBL6387790 | 0.80 | ALOX12 (0.36) | LMNA | |
| SCHEMBL8745048 | 0.78 | NAAA (0.35) | — | |
| SCHEMBL6511005 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL6508420 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL6893159 | 0.75 | — | — | |
| SCHEMBL6512880 | 0.71 | LMNA (0.39) | LMNA | |
| SCHEMBL3286023 | 0.70 | NAAA (0.30) | — | |
| SCHEMBL6508451 | 0.70 | LMNA (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068420-A1 | UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | claimed |
| WO-2005068420-A1 | UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | disclosed |