Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976260 | 0.92 | CASP3 (0.42) | PTGER1KCNA3KCNA5CASP3ALDH1A1 | |
| SCHEMBL3976257 | 0.83 | KIFC1 (0.49) | PTGER1KCNA3 | |
| SCHEMBL3973838 | 0.82 | ABCG2 (0.45) | PTGER1KCNA3CASP3 | |
| SCHEMBL6511059 | 0.81 | KIFC1 (0.47) | PTGER1KCNA3MCL1 | |
| SCHEMBL5926517 | 0.81 | CYP26A1 (0.41) | KCNA5 | |
| SCHEMBL3977295 | 0.77 | TACR3 (0.40) | KCNA5PPARG | |
| SCHEMBL5926331 | 0.77 | CYP26A1 (0.44) | PTGER1KCNA3CASP3HTT | |
| SCHEMBL4255107 | 0.75 | PTGER4 (0.41) | — | |
| SCHEMBL5926269 | 0.75 | CTSA (0.41) | PTGER1CASP3HTT | |
| SCHEMBL3979330 | 0.74 | POLB (0.43) | KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014532-A1 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |