Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976257 | 0.98 | KIFC1 (0.49) | KIFC1GPR34PTGER1ITGB1ITGA4 | |
| SCHEMBL3973838 | 0.92 | ABCG2 (0.45) | KIFC1GPR34PTGER1ITGB1ITGA4 | |
| SCHEMBL5926509 | 0.88 | ITGA4 (0.44) | GPR34ITGB1ITGA4ITGB7MME | |
| SCHEMBL3976260 | 0.85 | CASP3 (0.42) | PTGER1PTGER4PTGER3PTGER2MCL1 | |
| SCHEMBL5926329 | 0.82 | KIFC1 (0.51) | KIFC1GPR34PTGER1ITGB1ITGA4 | |
| SCHEMBL3978720 | 0.81 | ITGA4 (0.44) | GPR34ITGB1ITGA4ITGB7MME | |
| SCHEMBL6511062 | 0.81 | PTGER1 (0.39) | PTGER1MCL1KCNA3 | |
| SCHEMBL5926268 | 0.80 | KIFC1 (0.49) | KIFC1GPR34PTGER1ITGB1ITGA4 | |
| SCHEMBL5927129 | 0.79 | GPR34 (0.57) | KIFC1GPR34ITGB1ITGA4ITGB7 | |
| SCHEMBL5926298 | 0.78 | ITGA4 (0.47) | GPR34ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014532-A1 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |