SCHEMBL6511103

SCHEMBL6511103

NCC(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.42
MME P08473 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
QRFPR Q96P65 2/20 0.34
CTSC P53634 2/20 0.32
ECE1 P42892 1/20 0.32
TLR2 O60603 1/20 0.32
TERT O14746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18569190 1.00 TGFBR1 (0.42) TGFBR1MMECA12CA1CA2
SCHEMBL31688106 0.86 QRFPR (0.41) TGFBR1MMECA12CA1CA2
SCHEMBL9952740 0.84 TGFBR1 (0.43) TGFBR1MMECA12CA1CA2
SCHEMBL783082 0.82 TGFBR1 (0.57) TGFBR1MMECA1CA2
SCHEMBL783083 0.82 TGFBR1 (0.57) TGFBR1MMECA1CA2
SCHEMBL29556650 0.82 TGFBR1 (0.57) TGFBR1MMECA1CA2
SCHEMBL24072884 0.80 CYP2C9 (0.43) TGFBR1MMECA12CA1CA2
SCHEMBL12779591 0.80 CYP2C9 (0.43) TGFBR1MMECA12CA1CA2
SCHEMBL15185954 0.80 TGFBR1 (0.41) TGFBR1MMECA12CA1CA2
SCHEMBL12228626 0.80 KDM4E (0.38) CA12CA1CA9CTSCECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296958-A1 GLYCOSYLATED CYCLIC ENDOMORPHIN ANALOGS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2025-09-25 US disclosed
EP-4531885-A1 GLYCOSYLATED CYCLIC ENDOMORPHIN ANALOGS The Administrators of The Tulane Educational Fund (US) 2025-04-09 EP disclosed
WO-2023235319-A1 GLYCOSYLATED CYCLIC ENDOMORPHIN ANALOGS THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2023-12-07 WO disclosed
WO-2023235232-A2 GLYCOSYLATED CYCLIC ENDOMORPHIN ANALOGS THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2023-12-07 WO disclosed
EP-4153319-A1 METHOD FOR OBTAINING AN EXTRACT OF SANDALWOOD, COMPOSITIONS COMPRISING SAME AND COSMETIC USES THEREOF ISP Investments LLC (US) 2023-03-29 EP disclosed
US-10905769-B2 Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2021-02-02 US disclosed
US-20050164515-A9 Biological control of nanoparticle nucleation, shape and crystal phase BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-07-28 US disclosed
EP-0789710-A1 PEPTIDES FOR ANTI-ALLERGY TREATMENT PEPTIDE THERAPEUTICS LIMITED (GB) 1997-08-20 EP disclosed
WO-1996014333-A1 PEPTIDES FOR ANTI-ALLERGY TREATMENT PEPTIDE THERAPEUTICS LIMITED (GB) 1996-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296958-A1 GLYCOSYLATED CYCLIC ENDOMORPHIN ANALOGS OPRD1, OGFR, OPRL1 TGFBR1 2797/4885MME 757/4885CA12 1806/4885
US-10905769-B2 Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use PLK1, POLR1E, POLK TGFBR1 3489/4885MME 1643/4885CA12 4781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.