SCHEMBL783082

SCHEMBL783082

NCC(=O)NC(CO)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.57
MME P08473 6/20 0.50
CA2 P00918 5/20 0.42
CA1 P00915 3/20 0.42
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
GNPAT O15228 1/20 0.38
CA4 P22748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556650 1.00 TGFBR1 (0.57) TGFBR1MMECA2CA1FNTA
SCHEMBL783083 1.00 TGFBR1 (0.57) TGFBR1MMECA2CA1FNTA
SCHEMBL4086458 0.92 TGFBR1 (0.50) TGFBR1MMECA2CA1
SCHEMBL29456599 0.92 TGFBR1 (0.50) TGFBR1MMECA2CA1
SCHEMBL8542259 0.86 TGFBR1 (0.48) TGFBR1MMECA2CA1FNTA
SCHEMBL31488806 0.86 TGFBR1 (0.48) TGFBR1MMECA2CA1FNTA
SCHEMBL4082387 0.86 TGFBR1 (0.48) TGFBR1MMECA2CA1FNTA
SCHEMBL29051058 0.86 MME (0.50) TGFBR1MMECA2GNPATCA4
SCHEMBL29414477 0.86 TGFBR1 (0.44) TGFBR1MMECA2CA1
SCHEMBL29051061 0.86 MME (0.50) TGFBR1MMECA2GNPATCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US claimed
CN-117106189-A Metal organic framework artificial hydrolase and preparation method and application thereof 华南理工大学 2023-11-24 CN claimed
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-10-15 US claimed
EP-2925771-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES Council of Scientific & Industrial Research (IN) 2015-10-07 EP claimed
WO-2014083578-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESERACH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2014-06-05 WO claimed
EP-2262521-B1 OPHTHALMIC COMPOSITIONS COMPRISING A DIPEPTIDE WITH A GLYCINE MOIETY BAUSCH & LOMB (US) 2014-02-26 EP claimed
EP-2262521-A1 OPHTHALMIC COMPOSITIONS COMPRISING A DIPEPTIDE Bausch & Lomb Incorporated (US) 2010-12-22 EP claimed
WO-2009120562-A1 OPHTHALMIC COMPOSITIONS COMPRISING A DIPEPTIDE BAUSCH & LOMB INCORPORATED (US) 2009-10-01 WO claimed
US-20090247469-A1 OPHTHALMIC COMPOSITIONS COMPRISING A DIPEPTIDE BAUSCH HEALTH AMERICAS, INC. 2009-10-01 US claimed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP claimed
US-6503413-B2 Polyalkylene polysiloxane, buffering agent, aqueous carrier THE PROCTER & GAMBLE COMPANY 2003-01-07 US claimed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP claimed
US-6429220-B1 COMPRISES AN ISOTHIAZOLONE COMPOUND AND AN AMINOCARBOXYLIC ACID KURITA WATER INDUSTRIES LTD. (JP) 2002-08-06 US claimed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 US claimed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 US claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP TGFBR1 3218/4885MME 824/4885CA2 4132/4885
US-20020010154-A1 Compositions comprising cyclodextrin FFAR4, FRG1, FGB TGFBR1 1760/4885MME 3638/4885CA2 2473/4885
US-20090247469-A1 OPHTHALMIC COMPOSITIONS COMPRISING A DIPEPTIDE GPKOW, GLMN, ARGLU1 TGFBR1 3647/4885MME 304/4885CA2 1822/4885
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF CNR2, SRM, CNR1 TGFBR1 3020/4885MME 1788/4885CA2 1282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.